How to preserve peptide nucleic acid | peptide nucleic acid containing azobenzene unit (n-pna) | 99Tcm labeled c-myc mRNA

How to preserve peptide nucleic acid | Peptide nucleic acids containing azobenzene units (N-PNA)|99Tcm Mark c-myc mRNA

service ： Peptide nucleic acid PNA Custom service
solubility ： Soluble in DMF、DMSO etc.
state ： solid / Powder / solution
preservation ： cold storage
purpose ： scientific research

Peptide nucleic acid (PeptideNucleicAcid,PNA) It's a kind of DNA Analogues , Structurally, it retains DNA Base and deoxyribose , Just the original ribose - The phosphate skeleton is replaced by an amide bond skeleton similar to a peptide bond . therefore ,PNA Still follow the principle of complementary base pairing , And the skeleton turns from negative to nearly neutral , Weakened the electrostatic repulsion between double stranded nucleic acids , bring LNA And DNA or RNA The binding stability and specificity of are greatly improved . and ,PNA The amide bond skeleton of is not easy to be hydrolyzed by nuclease and protease , Make it stable in vivo and in vitro .

 

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Small make up axc,2022.07.20