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PNA peptide nucleic acid modified polypeptide z-gly-pro-pna | d-phe-pip-arg-pna | TOS Gly Pro Arg PNA
2022-07-23 09:39:00 【Meet Qi Yue】
PNA Peptide nucleic acid modifies polypeptide Z-Gly-Pro-pNA|D-Phe-Pip-Arg-pNA|Tos-Gly-Pro-Arg-pNA
Peptide nucleic acid (PNA,peptidenucleicacid) It's a kind of DNA Analogues , Can identify and combine DNA or RNA Sequence , Form a stable double helix structure . because PNA No negative charge , And DNA and RNA There is no electrostatic repulsion between , Therefore, the stability and specificity of the binding are greatly improved and are not hydrolyzed by nuclease and protease .PNA It can be applied to the following fields :
1)miRNA
2) Antisense drug research
3) Tools for molecular biology and functional genomics
4) With molecular probes :telomere Of FISH probe ;Lightup probe ;SNP Identification probe ;Microarray probe ;Nucleicacidbiosensor probe

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Small make up axc,2022.07.20
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